anti-angiogenesis相关论文
Combretastatin A4 induces impairment of endothelial cells function and inhibits angiogenesis by inhi
the formation of new blood vessels by endothelial cells from existing microvessels,is a critical process in solid tumor.......
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Aim: A tetrahydroisoquinoline-based hydroxamic acid derivative (ZYJ-34c) as histone deacetylase inhibitor, inhibited the......
Cysteine-rich secretory proteins(CRISPs),characterized by 16 conserved cysteines,are distributed in a wide range of orga......
Angiogenesis Inhibitor Endostar Prevents Vasa Vasorum Neovascularization in the Swine Atherosclerosi
Objective Vasa vasorum neovascularization is a key feature of atherosclerosis and strongly associated with inflammatory ......
Restrain Effect of Three Anti-tumor Monomers Extracted from Chinese Medicine on The Growth of ECV304
Objective: Melittin,norcantharidin and bufalin are three extracts from Chinese herbal medicine in clinical application w......
Effects of Albizia Julibrissin Bark Extract on Anti-Angiogenesis in Vitro and in Vivo and Related Me
Purpose:In this study,we examined inhibiting angiogenic effects of Albiziajulibrissin bark extract (AJBE) in vitro and i......
Dual Functions of Cyclometalated Iridium(Ⅲ)Complexes:Anti-metastasis and Lysosome-damaged Photodynam
Cancer metastasis and drug resistance lead to treatment difficulty and increasing mortality rates....
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A Novel Structural Fucosylated Chondroitin Sulfate from Holothuria Mexicana and ITS Effects on Growt
Fucosylated chondroitin sulfate (FCS),a structurally distinct glycosaminoglycan extracted from the body wall of sea ......
为研究一种全人源抗VEGF单克隆抗体在体外和体内的抑制血管生成和抗肿瘤活性,利用细胞划痕实验检测抗体抑制人脐静脉内皮细胞(HUVE......
肺癌是全球病死率最高的恶性肿瘤,晚期肺癌生存率更低.目前对于无驱动基因突变的肺癌,标准治疗方案为化疗,但疗效欠佳,生存获益低,......
Synergistic anti-tumor effect of recombinant chicken fibroblast growth factor receptor-1-mediated an
AIM: To evaluate whether the combination of recombinant chicken fibroblast growth factor receptor -1(FGFR-1) protein vac......
Since recombinant human endostatin (rh-endostatin; Endostar) has been listed 5 years, clinicians have combined it with c......
Continued application of Endostar combined with chemotherapy in advanced hemangioendothelioma of bon
By one case of hemangioendothelioma of bone accompanying pulmonary metastasis was treated with rh-enostatin injection (E......
Angiogenesis occurs during the process of tumor growth, invasion and metastasis, and is essential for the survival of so......
血管内皮生长因子(VEGF)是一种重要的血管生成调节因子.血管内皮生长因子受体2(VEGFR2,人VEGFR2也称为Kinase insert domain-conta......
,Study progression of anti-angiogenetic therapy and its combination with other agents for the treatm
Hepatocellular carcinoma (HCC) is a common malignancy worldwide and is especially prevalent in the Chinese population. T......
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Tumor vascular normalization has been proposed as a therapeutic strategy for malignant neoplasms,which can also interpre......
Objective:To study the mechanism of Wnt/β-catenin signaling pathway in the enhanced malignant phenotype of A549 cells o......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Anti-angiogeneic Target Therapy for Cancer with Vaccine Based on the Recombinant Chicken FGFR-1 in T
To explore the anti-tumor effect of immunotherapy with recombinant protein vaccine based on FGFR-1 of chicken (cFR-1) in......
Objective To investigate endostatin gene therapy of rat corneal neovascularization induced by acid cauterization. Method......
Effects of cloned tumstatin-related and angiogenesis-inhibitory peptides on proliferation and apopto
Background Tumstatin is a recently developed endogenous vascular endothelial growth inhibitor that can be applied as an ......
Multi-targeted tyrosine kinase inhibitor sunitinib: a novel strategy for sporadic malignant pheochro
Sporadic malignant pheochromocytoma,a rare disease with poor prognosis,is always difficult to treat due in part to lack ......
Numerical simulation of solid tumor angiogenesis with Endostatin treatment: a combined analysis of i
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Continued application of Endostar combined with chemotherapy in advanced hemangioendothelioma of bon
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
In human patients,drugs that block tumor vessel growth are widely used to treat a variety of cancer types.Many rigorous ......
Clinical Observation of Bevacizumab Combined with S-1 in the Treatment of Pretreated Advanced Esopha
Objective To investigate the clinical effects and safety of bevacizumab combined with S-1 as the second-line treatment o......
随着全球老龄化的日益明显,脉络膜新生血管(CNV)特别是继发于年龄相关性黄斑变性的CNV日益成为一种严重的社会医学负担.近年来对于......
Anti-angiogeneic Target Therapy for Cancer with Vaccine Based on the Recombinant Chicken FGFR-1 in T
To explore the anti-tumor effect of immunotherapy with recombinant protein vaccine based on FGFR-1 of chicken (cFR-1) in......
目的 探讨长春瑞滨联合西妥昔单抗对体内外血管生成的抑制作用.方法 以人肺腺癌细胞株A549为对照,采用四甲基偶氮唑蓝(MTT)法,观察......
白细胞介素12(IL-12)是20世纪末发现的一种异源二聚体分子,被认为是调节细胞免疫的关键因子,与消化道系统肿瘤关系密切.近期国内外......
门脉高压(portal hypertension,PHT)是慢性肝病肝硬化患者主要的并发症之一,近年来,新生血管形成在PHT中的作用受到越来越多学者的......
Synergistic anti-tumor effect of recombinant chicken fibroblast growth factor receptor-1-mediated an
AIM: To evaluate whether the combination of recombinant chicken fibroblast growth factor receptor -1(FGFR-1) protein vac......
Effects of cloned tumstatin-related and angiogenesis-inhibitory peptides on proliferation and apopto
Background Tumstatin is a recently developed endogenous vascular endothelial growth inhibitor that can be applied as an ......
Multi-targeted tyrosine kinase inhibitor sunitinib: a novel strategy for sporadic malignant pheochro
Sporadic malignant pheochromocytoma,a rare disease with poor prognosis,is always difficult to treat due in part to lack ......
Numerical simulation of solid tumor angiogenesis with Endostatin treatment: a combined analysis of i
To investigate the influence of anti-angiogenesis drug Endostatin on solid tumor angiogenesis, a mathematical model of t......
选择两段血小板反应素(TSP-1)中抑制血管再生的活性片段,设计两对引物,使用RT-PCR的方法从人血细胞中进行克隆并对获得片段进行测......
实体瘤当生长到一定的体积时必然伴随着血管生成.1971年,Folkman[1]最早提出肿瘤生长是血管依赖性的.他认为肿瘤血管生成是肿瘤生......
目的：研究白头翁醇提物对昆明小鼠H22肝癌细胞皮下移植瘤的抗血管生成作用。方法：建立鼠H22肝癌细胞小鼠皮下移植瘤模型,给予不同剂......
目的 研究隐丹参酮（Cryptotanshinone）的抗肿瘤活性及其抗血管生成的活性机制,为隐丹参酮治疗肿瘤提供数据支持。方法 培养结肠癌细......
研究了白藜芦醇在体外和体内实验中抗血管生成的活性．研究发现，白藜芦醇在体外实验中能明显抑制ECV304细胞的增殖(作用48h的IC50是59......
本文旨在寻找一种的^99Tc^m标记的抗肿瘤血管化的显像剂。将具抗肿瘤血管化的多肽适当修饰后，用^99Tc^m标记，并在肿瘤荷鼠体内筛选比......
目的为阿帕替尼的临床应用提供参考。方法总结阿帕替尼的作用机制、在晚期原发性肝癌的应用、治疗原发性肝癌的剂量,并进行安全性......
